There is a huge variety of positions in clinical research, with high demands on professional and personal qualifications. In the magic triangle, quality - time - budget, wise decisions have to be made. Within the "cross - functional" teams different visions and professions have to be harmonized. In contact with doctors and authorities it is necessary to maintain a good balance between diplomacy and assertiveness. At the same time the employees need to find creative solutions every day in a highly regulated area, in order to carry out demanding studies while respecting the often contradictory interests of all parties involved.